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Coordinated Transcriptional and Catabolic Programs Support Iron-Dependent Adaptation to RAS-MAPK Pathway Inhibition in Pancreatic Cancer.
Ravichandran M, Hu J, Cai C, Ward NP, Venida A, Foakes C, Kuljanin M, Yang A, Hennessey CJ, Yang Y, Desousa BR, Rademaker G, Staes AAL, Cakir Z, Jain IH, Aguirre AJ, Mancias JD, Shen Y, DeNicola GM, Perera RM. Ravichandran M, et al. Among authors: hennessey cj. Cancer Discov. 2022 Sep 2;12(9):2198-2219. doi: 10.1158/2159-8290.CD-22-0044. Cancer Discov. 2022. PMID: 35771494 Free PMC article.
NCOA4-Mediated Ferritinophagy Is a Pancreatic Cancer Dependency via Maintenance of Iron Bioavailability for Iron-Sulfur Cluster Proteins.
Santana-Codina N, Del Rey MQ, Kapner KS, Zhang H, Gikandi A, Malcolm C, Poupault C, Kuljanin M, John KM, Biancur DE, Chen B, Das NK, Lowder KE, Hennessey CJ, Huang W, Yang A, Shah YM, Nowak JA, Aguirre AJ, Mancias JD. Santana-Codina N, et al. Among authors: hennessey cj. Cancer Discov. 2022 Sep 2;12(9):2180-2197. doi: 10.1158/2159-8290.CD-22-0043. Cancer Discov. 2022. PMID: 35771492 Free PMC article.